Severed

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Compression induced damage on in-situ severed and intact nerves.

The effect of rapid as well as sustained compressive forces applied to the surface of intact and severed peroneal nerves of rabbits was studied. Considerable effort was taken to ensure a quantitative and consistent experimental paradigm. Stimuli were delivered to the sciatic nerve, and the compound action potential was recorded in the peroneal nerve, with compressive forces applied more proxima...

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Calpain activity promotes the sealing of severed giant axons.

A barrier (seal) must form at the cut ends of a severed axon if a neuron is to survive and eventually regenerate. Following severance of crayfish medial giant axons in physiological saline, vesicles accumulate at the cut end and form a barrier (seal) to ion and dye diffusion. In contrast, squid giant axons do not seal, even though injury-induced vesicles form after axonal transection and accumu...

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The Non-centrifugal Degeneration of Severed Peripheral Nerve

NEUMANN in 1868 proposed the idea that severed peripheral nerve degenerates centrifugally; i.e., the degenerative processes start at the cut end and progress slowly towards the periphery. This view, opposing the conception of simultaneous degeneration advanced by Lent in 1856, started a controversy as yet unsettled. Most of the arguments on both sides have been based on histological evidence-on...

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"If we can keep a severed head alive...".

not be a matter for criticism. The aim of the new society is to provide an alternative to the existing bodies, not to replace them, and nor is it to disadvantage any other elements of the profession. In his review of my book (3 September, p 629) Professor T J Hamblin stated, "In [Fleming's] view a device to perfuse a human head might lead to horrific consequences, and so he has developed a fien...

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Vesicle-mediated restoration of a plasmalemmal barrier in severed axons.

Ca(2+)-induced endocytotic vesicles undergo protein-mediated interactions to restore a selectively permeable barrier and propagated action potentials in severed invertebrate giant axons. Similar barrier-restoration phenomena observed in cultured mammalian cells with transected neurites suggest that cellular/molecular mechanisms that repair plasmalemmal damage are phylogenetically conserved.

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ژورنال

عنوان ژورنال: Streams of Consciousness

سال: 2019

ISSN: 2640-0049

DOI: 10.7191/soc.2019.1053